ScanBIC

The number of reads at each unique read position

combX

The number of case/tumor reads at each unique read position

combZ

tauHat

The null likelihood. Computed in the main routine.

lik0

nTotal

This computes mBIC for the current change point model. We then use this to determine the appropriate model complexity.

This is a method for DNA Copy Number Profiling using
Next-Generation Sequencing. It has new model and test
statistics based on non-homogeneous Poisson Processes with
change point models. It uses an adaptation of Circular Binary
Segmentation. Also included are methods for point-wise Bayesian
Confidence Interval and model selection method for the
change-point model. A case and a control sample reads (normal
and tumor) are required.

ScanBIC: Compute the modified BIC for change-point models

Description

Usage

Arguments

Value

Details

See Also