clusterProfiler (version 3.0.4)

enrichGO: GO Enrichment Analysis of a gene set. Given a vector of genes, this function will return the enrichment GO categories after FDR control.

Description

GO Enrichment Analysis of a gene set. Given a vector of genes, this function will return the enrichment GO categories after FDR control.

Usage

enrichGO(gene, OrgDb, keytype = "ENTREZID", ont = "MF", pvalueCutoff = 0.05, pAdjustMethod = "BH", universe, qvalueCutoff = 0.2, minGSSize = 10, maxGSSize = 500, readable = FALSE)

Arguments

gene

a vector of entrez gene id.

OrgDb

OrgDb

keytype

keytype of input gene

ont

One of "MF", "BP", and "CC" subontologies.

pvalueCutoff

Cutoff value of pvalue.

pAdjustMethod

one of "holm", "hochberg", "hommel", "bonferroni", "BH", "BY", "fdr", "none"

universe

background genes

qvalueCutoff

qvalue cutoff

minGSSize

minimal size of genes annotated by Ontology term for testing.

maxGSSize

maximal size of genes annotated for testing

readable

whether mapping gene ID to gene Name

Value

A enrichResult instance.

See Also

enrichResult-class, compareCluster

Examples

## Not run: 
# 	data(gcSample)
# 	yy <- enrichGO(gcSample[[1]], 'org.Hs.eg.db', ont="BP", pvalueCutoff=0.01)
# 	head(summary(yy))
# 	plot(yy)
# ## End(Not run)