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MCPMod (version 1.0-10.1)

exponential: Exponential (power) model

Description

The model function for the exponential model is defined as $$ f(d,\theta)=E_0+E_1(exp(d/\delta)-1)$$

Usage

exponential(dose, e0, e1, delta)

Arguments

dose

Dose variable

e0

Placebo effect

e1

E1 parameter

delta

Delta parameter, controlling the convexity of the model.

Value

Response value

Details

This model is intended to capture a possible sub-linear or a convex dose-response relationship.

References

Pinheiro, J. C., Bretz, F. and Branson, M. (2006). Analysis of dose-response studies - modeling approaches, in N. Ting (ed.). Dose Finding in Drug Development, Springer, New York, pp. 146--171

See Also

logistic, sigEmax, linlog, linear, quadratic, emax, betaMod