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sybil (version 2.2.0)

geneDel: Get Gene-Reaction Association

Description

The function geneDel returns the fluxes which are effected by a particular combination of genes.

Usage

geneDel(model, genes, checkId = FALSE)

Arguments

model

An object of class modelorg.

genes

A vector of character strings of gene id's used in model, or an integer vector with indices to gene id's in allGenes(model).

checkId

Boolean. If set to TRUE, argument genes will be checked wether it fits to model (e.g. are all genes existing). If set to FALSE, genes must contain indices of gene id's in model, e.g. in calls from optimizer.

Value

An numeric vector of pointers to reaction id's in model or NULL, if no fluxes are effected by the gene deletion.

Details

The function geneDel checks for a set of gene id's in gene on which fluxes a deletion of this set of genes has an effect.

References

Edwards, J. S., Ibarra, R. U. and Palsson, B. <U+00D8>. (2001) In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat Biotechnol 19, 125--130.

See Also

optimizer