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Epi (version 2.59)

Statistical Analysis in Epidemiology

Description

Functions for demographic and epidemiological analysis in the Lexis diagram, i.e. register and cohort follow-up data. In particular representation, manipulation, rate estimation and simulation for multistate data - the Lexis suite of functions, which includes interfaces to 'mstate', 'etm' and 'cmprsk' packages. Contains functions for Age-Period-Cohort and Lee-Carter modeling and a function for interval censored data and some useful functions for tabulation and plotting, as well as a number of epidemiological data sets.

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Version

Install

install.packages('Epi')

Monthly Downloads

7,473

Version

2.59

License

GPL-2

Maintainer

Bendix Carstensen

Last Published

January 13th, 2025

Functions in Epi (2.59)

N2Y

Create risk time ("Person-Years") in Lexis triangles from population count data.
B.dk

Births in Denmark by year and month of birth and sex
NArray

Set up an array of NAs, solely from the list of dimnames
Lexis

Create a Lexis object of follow-up
LCa.fit

Fit Lee-Carter-type models for rates to arbitrarily shaped observations of rates in a Lexis diagram.
DMconv

Conversion to diabetes
DMepi

Epidemiological rates for diabetes in Denmark 1996--2015
Life.lines

Compute dates/ages for life lines in a Lexis diagram
DMlate

The Danish National Diabetes Register.
Lexis2msm

Convert a Lexis obejct to a data set suitable for input to the msm:msm function.
Epi

Epi: Functions for manipulation and statistical analysis of epidemiological data
Lexis.diagram

Plot a Lexis diagram
addCov.Lexis

Add covariates (typically clinical measurements) taken at known times to a Lexis object.
addDrug.Lexis

Expand a Lexis object with information of drug exposure based on purchase dates and -amounts
Y.dk

Population risk time in Denmark
Termplot

A wrapper for termplot that optionally (but by default) exponentiates terms, and plot them on a common log-scale. Also scales x-axes to the same physical scale.
Lexis.lines

Draw life lines in a Lexis diagram.
M.dk

Mortality in Denmark 1974 ff.
N.dk

Population size in Denmark
Relevel

Reorder and combine levels of a factor
S.typh

Salmonella Typhimurium outbreak 1996 in Denmark.
Icens

Fits a regression model to interval censored data.
bdendo

A case-control study of endometrial cancer
apc.frame

Produce an empty frame for display of parameter-estimates from Age-Period-Cohort-models.
Ns

Natural splines - (cubic splines linear beyond outermost knots) with convenient specification of knots and possibility of centering, detrending and clamping.
ROC

Function to compute and draw ROC-curves.
apc.LCa

Fit Age-Period-Cohort models and Lee-Carter models with effects modeled by natural splines.
apc.fit

Fit an Age-Period-Cohort model to tabular data.
bootLexis

Create a bootstrap sample of persons (as identified by lex.id) from a Lexis object
ccwc

Generate a nested case-control study
ci.Crisk

Compute cumulative risks and expected sojourn times from models for cause-specific rates.
cal.yr

Functions to convert character, factor and various date objects into a number, and vice versa.
ci.cum

Compute cumulative sum of estimates.
brv

Bereavement in an elderly cohort
ci.eta

Linear predictor (eta) from a formula, coefficients, vcov and a prediction frame.
boxes.MS

Draw boxes and arrows for illustration of multistate models.
crr.Lexis

Fit a competing risks regression model (Fine-Gray model) using a Lexis object)
births

Births in a London Hospital
blcaIT

Bladder cancer mortality in Italian males
clogistic

Conditional logistic regression
contr.cum

Contrast matrices
ci.lin

Compute linear functions of parameters with standard errors and confidence limits, optionally transforming to a different scale.
cutLexis

Cut follow-up at a specified date for each person.
diet

Diet and heart data
detrend

Projection of a model matrix on the orthogonal complement of a trend or curvature.
effx

Function to calculate effects
effx.match

Function to calculate effects for individually matched case-control studies
erl

Compute survival functions from rates and expected residual lifetime in an illness-death model as well as years of life lost to disease.
foreign.Lexis

Create a data structures suitable for use with packages mstate or etm.
float

Calculate floated variances
ci.pd

Compute confidence limits for a difference of two independent proportions.
expand.data

Function to expand data for regression analysis of interval censored data.
ftrend

Fit a floating trend to a factor in generalized linear model
fit.baseline

Fit a piecewise contsnt intesity model for interval censored data.
gen.exp

Generate covariates for drug-exposure follow-up from drug purchase records.
lgrep

Convenience versions of grep
fit.add

Fit an additive excess risk model to interval censored data.
ewrates

Rates of lung and nasal cancer mortality, and total mortality.
fit.mult

Fits a multiplicative relative risk model to interval censored data.
hivDK

hivDK: seroconversion in a cohort of Danish men
lls

Functions to manage and explore the workspace
in.span

Is x in the column span of matrix A and what columns are linearly dependent?
lungDK

Male lung cancer incidence in Denmark
gmortDK

Population mortality rates for Denmark in 5-years age groups.
legendbox

Draw a box with text explaining the numbers in and between boxes from boxes.MS and boxes.Lexis
apc.lines

Plot APC-estimates in an APC-frame.
lep

An unmatched case-control study of leprosy incidence
mat2pol

Plot columns of a matrix as stacked areas.
nice

Nice breakpoints for axes on plots
nickel

A Cohort of Nickel Smelters in South Wales
mortDK

Population mortality rates for Denmark in 1-year age-classes.
ncut

Function to group a variable in intervals.
matshade

Plot confidence intervals as shaded areas around lines.
mcutLexis

Cut follow-up at multiple event dates and keep track of order of events
merge.Lexis

Merge a Lexis object with a data frame
plotCIF

Plotting Aalen-Johansen curves for competing events
mh

Mantel-Haenszel analyses of cohort and case-control studies
occup

A small occupational cohort
pc.lines

Plot period and cohort effects in an APC-frame.
paths.Lexis

Generate paths travelled through a Lexis multistate model data frame.
harm

Create a basis of harmonic functions.
plot.Lexis

Lexis diagrams
mod.Lexis

Fit intensity models to follow-up data in Lexis objects
pctab

Create percentages in a table
plotevent

Plot Equivalence Classes
plotEst

Plot estimates with confidence limits (forest plot)
plot.apc

Plot the estimates from a fitted Age-Period-Cohort model
poisreg

Family Object for Poisson Regression
rateplot

Functions to plot rates from a table classified by age and calendar time (period)
simLexis

Simulate a Lexis object representing follow-up in a multistate model.
rm.tr

Remove transitions from a Lexis object.
rcutLexis

A function to cut follow-up at intermediate event times.
pr

Diabetes prevance as of 2010-01-01 in Denmark
projection.ip

Projection of columns of a matrix.
splitLexis

Split follow-up time in a Lexis object
stack.Lexis

Functions to facilitate analysis of multistate models.
summary.Lexis

Summarize transitions and risk time from a Lexis object
testisDK

Testis cancer incidence in Denmark, 1943--1996
timeScales

The time scales of a Lexis object
cbind.Lexis

Combining a Lexis objects with data frames or other Lexis objects
unLexis

Remove Lexis attributes from a Lexis object.
steno2

Clinical trial: Steno2 baseline and follow-up.
thoro

Thorotrast Study
subset.Lexis

Subsetting Lexis (and stacked.Lexis) objects
timeBand

Extract time band data from a split Lexis object
twoby2

Analysis of a two by two table
transform.Lexis

Transform a Lexis (or stacked.Lexis) object
entry.Lexis

Time series and other methods for Lexis objects
stat.table

Tables of summary statistics
stattable.funs

Special functions for use in stat.table
AaJ.Lexis

The Aalen-Johansen estimator of state probabilities from a multistate Lexis object.
BrCa

Clinical status, relapse, metastasis and death in 2982 women with breast cancer.