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AGSDest (version 2.3.4)

Estimation in Adaptive Group Sequential Trials

Description

Calculation of repeated confidence intervals as well as confidence intervals based on the stage-wise ordering in group sequential designs and adaptive group sequential designs. For adaptive group sequential designs the confidence intervals are based on the conditional rejection probability principle. Currently the procedures do not support the use of futility boundaries or more than one adaptive interim analysis.

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Version

Install

install.packages('AGSDest')

Monthly Downloads

134

Version

2.3.4

License

GPL (>= 2)

Last Published

March 7th, 2022

Functions in AGSDest (2.3.4)

AGSDest

Estimation in adaptive group sequential trials
as.AGST

as Adaptive Group Sequential Trial
cp

coditional power of a GSD
pvalue

Calculates the p-value
cer

Conditional type I error rate (also called conditional rejection probability)
AGSTobj

Adaptive group sequential trial object (AGSTobj)
GSTobj

Group sequential trial object (GSTobj)
adapt

Adaptations in group sequential trials
plan.GST

Plans a group sequential trial (GST)
seqconfint

Calculates confidence interval
as.GST

as Group Sequential Trial
typeIerr

type I error rate of a GSD