HLA_data

<p>A synthetic dataset of HLA genotypes for using bigdawg.</p>

datasets

Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.

Steven Mack

BIGDAWG

Case-Control Analysis of Multi-Allelic Loci

HLA_data function

<p>A data frame with 2000 rows and 14 variables</p>

HLA_data: Example HLA Dataset

Description

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