BTR (version 1.2.4)

initialise_raw_data: Initialise raw data

Description

This function initialise raw gene expression values in a matrix. Return either a matrix of (1) continuous values or (2) binary values. Note that kmeans clustering as binarisation only works well if the data has a bimodal distribution.

Usage

initialise_raw_data(x, max_expr = "high", uni_thre = 0.2, scale = T, discretised = F)

Arguments

x

matrix. Numeric data of gene expression.

max_expr

character. Specify whether max expression value is the lowest (as in qPCR), or the highest (as in RNAseq and microarray). Option: 'low', 'high'. Default to 'high'.

uni_thre

numerical. Speficy threshold for unimodality test. Default to 0.2.

scale

logical. Whether to scale the data to a range of 0-1. Default to T.

discretised

logical. Whether to return discretised data. Default to F.