testMeth

A list containing coverage as 1st element and non-conversion
ratio as 2nd element, for one C position.

ratio (Poisson parameter / coverage)

lambda

<code>testMeth</code> applies poisson.test to a sample from bisulfite-treated RNA experiment taking into account the ratio (Poisson parameter / coverage) characteristic of this sample.

Bisulfite-treated RNA non-conversion in a set of samples is
analysed as follows : each sample's non-conversion distribution is
identified to a Poisson distribution. P-values adjusted for multiple
testing are calculated in each sample. Combined non-conversion P-values
and standard errors are calculated on the intersection of the set of
samples. For further details, see C Legrand, F Tuorto, M Hartmann,
R Liebers, D Jakob, M Helm and F Lyko (2017) <doi:10.1101/gr.210666.116>.

testMeth: Apply poisson.test to BS coverage and non-conversion ratio.

Description

Usage

Arguments

Value

Details