S4BuyseTest-class

<p>A <code>BuyseTest</code> output is reported in a <code>S4BuyseTest</code> object.</p>

classes

Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better/worse/equivalently than a random observation drawn from the other group. Summary statistics such as the net treatment benefit, win ratio, or win odds are then deduced from these probabilities. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks.

Brice Ozenne

BuyseTest

Generalized Pairwise Comparisons

Eva Cantagallo

William Anderson

Julien Peron

Johan Verbeeck

S4BuyseTest-class function

Author

Class "S4BuyseTest" (output of BuyseTest) — S4BuyseTest-class

Class "S4BuyseTest" (output of BuyseTest)

S4BuyseTest-class: Class "S4BuyseTest" (output of BuyseTest)

Description

Arguments

Author

See Also