CellChat (version 1.0.0)

computeExpr_antagonist: Modeling the effect of antagonist on the ligand-receptor interaction

Description

Modeling the effect of antagonist on the ligand-receptor interaction

Usage

computeExpr_antagonist(
  data.use,
  pairLRsig,
  cofactor_input,
  group,
  index.antagonist,
  Kh,
  FunMean,
  n
)

Arguments

data.use

data matrix

pairLRsig

the L-R interactions

cofactor_input

the cofactor_input from CellChatDB

group

a factor defining the cell groups

index.antagonist

the index of antagonist in the database

Kh

a parameter in Hill function

FunMean

the function for computing mean expression per group

n

Hill coefficient

Value