CellChat (version 1.0.0)

extractEnrichedLR_internal: Identify all the significant interactions (L-R pairs) and related signaling genes for a given signaling pathway

Description

Identify all the significant interactions (L-R pairs) and related signaling genes for a given signaling pathway

Usage

extractEnrichedLR_internal(
  net,
  LR,
  DB,
  signaling,
  enriched.only = TRUE,
  thresh = 0.05
)

Arguments

net, LR, DB

object@net object@LR object@DB

signaling

a char vector containing signaling pathway names for searching

enriched.only

whether only return the identified enriched signaling genes in the database. Default = TRUE, returning the significantly enriched signaling interactions

thresh

threshold of the p-value for determining significant interaction

Value

a list: list(geneLR, pairLR.name.use)