Crossover (version 0.1-22)

contrMat2: Create the design matrix, variance-covariance matrix, the variance of each pairwise comparison and the efficicency of each pairwise comparison for a cross-over design

Description

Function to read in a cross-over design and create the design matrix X, the variance of each pairwise comparison and the efficicency of each pairwise comparison.

Usage

contrMat2(
  type,
  v,
  model,
  eff.factor = rep(1, length(parameterCount(model, v)))
)

Value

A contrast matrix

Arguments

type

Type of contrast. A character vector containing the following: "Dunnett", "Tukey", "none". If the length is 1, this contrast is only applied for the treatment effects and for carry-over effects a "Tukey" contrast is used. Otherwise the specified contrasts are used, see also the examples.

v

Number of treatments

model

Model - one of the following: 1) "Standard additive model", 2) "Second-order carry-over effects", 3) "Full set of interactions", 4) "Self-adjacency model", 5) "Placebo model", 6) "No carry-over into self model", 7) "Treatment decay model", 8) "Proportionality model", 9) "No carry-over effects". Can be specified as number or as character string.

eff.factor

Weight applied to the different sub contrast matrices. A warning is given if it does not sum up to one. See examples.

Author

Kornelius Rohmeyer

Details

See the vignette of this package for further details.

Examples

contrMat2("Tukey", v=3, model=1)
contrMat2("Dunnett", v=3, model=1)
contrMat2(c("Dunnett", "Dunnett"), v=3, model=1)
contrMat2(c("Dunnett", "none"), v=3, model=1)
contrMat2(c("Dunnett", "none", "none"), v=3, model=8)
contrMat2("Dunnett", v=3, model=1, eff.factor=c(0.9, 0.1))
contrMat2("Dunnett", v=3, model=8, eff.factor=c(0.5, 0.3, 0.2))