DATAstudio (version 1.2.1)

cortical: Brain Shape Data

Description

Axial brain slices gathered via magnetic resonance images (MRI) with 500 points on each outline, for 30 schizophrenia patients and 38 healthy controls.

Usage

cortical

Format

The cortical list has the following variables:

age

Age, in years.

group

Control patient (Con) or schizophrenia patient (Scz).

sex

Male (1) or female (2).

symm

Symmetry score obtained from raw 3D brain surface.

x and y

Coordinates of slice from brain surface that intersects the AC (anterior commissure) and PC (posterior commissure).

cortical\$r

500 radii from angular polar coordinates.

Details

The data were gathered from a neuroscience study conducted at the University of British Columbia, Canada, and documented in Brignell et al. (2010) and Martos and de Carvalho (2018). Each brain was registered into the so-called Talairach space so that brains can be compared on the same three-dimensional referential coordinate space.

References

Brignell, C.J., Dryden, I.L., Gattone, S.A., Park, B., Leask, S., Browne, W.J., and Flynn, S. (2010) Surface shape analysis, with an application to brain surface asymmetry in schizophrenia. Biostatistics, 11, 609-630.

Martos, G. and de Carvalho, M. (2018) Discrimination surfaces with application to region-specific brain asymmetry analysis. Statistics in Medicine, 37, 1859-1873.

Examples

  ## Martos and de Carvalho (2018; Fig 1 a)
  library(scales)
  data(cortical)
  m <- 500  
  n <- 68
  plot(cortical$r[,1] * cos(2 * pi * 1:m / m),
       cortical$r[,1] * sin(2 * pi * 1:m / m) , type = "l",
       col = alpha("gray", 1 / n), xlab = "z", ylab = "x")
  for(i in 2:n) 
  lines(cortical$r[, i] * cos(2 * pi * 1:m / m),
        cortical$r[, i] * sin(2 * pi * 1:m / m), type = "l",
        col = alpha("gray", i / n))