DCGL (version 2.1.2)

tf2target: The dataset of human Transcription Factors regulate potential target genes

Description

There are 19,9950 TF-to-target interaction pairs downloaded from UCSC (http://genome.ucsc.edu/).

Usage

data(tf2target)

Format

A data frame with 19,9950 observations 2 variables.

• tf2target A data frame with 19,9950 observations 2 columns. TF-to-target interaction pairs.

Details

We downloaded tfbsConsSites and tfbsConsFactors files from UCSC (http://genome.ucsc.edu). tfbsConsSites gives the coordinate information of all TFs acted on, tfbsConsFactors gives TFs identifier information. We can predict all the TFs to potential targets relationship based on refGene file which also came from UCSC and contained genes' position information of hg18. There are 199 TFs and 19,9950 TF-to-target interactions.

Examples

data(tf2target)
tf2target[1:3,] # TFs (column 1) act on potential target genes (column 2)