Learn R Programming

DOQTL (version 1.8.0)

cc.trans.probs: Transition probabilities for CC mice.

Description

Thie function returns the transition probabilities for fully inbred Collaborative Cross mice.

Usage

cc.trans.probs(states, snps, chr = c(1:19, "X"), sex = c("M", "F"))

Arguments

states
Character vector containing the two letter codes (i.e. AA, BB, CC, etc.) for the homozygous states.
snps
Data.frame containing the marker locations. SNP ID, chromosome, Mb anc cM locations in columns 1 through 4, respectively. Not required for DO.
chr
Character containing the chromosome.
sex
Character that is either M or FALSE, indicating the sex to use. Only relevant on X chromosome.

Value

A matrix of transition probabilities between genotype states.

Details

This function calculates the transition probabilities for fully inbred CC mice between two markers. It uses the equations for eight way RILs by sib mating.

References

The genomes of recombinant inbred lines. Broman KW. Genetics. 2005 FALSEeb;169(2):1133-46. Epub 2004 Nov 15. Erratum in: Genetics. 2006 Aug;173(4):2419. PMID: 15545647

Examples

Run this code
  ## Not run:  cc.trans.probs(states = states, snps = snps, chr = 1) 

Run the code above in your browser using DataLab