DTAT (version 0.3-4)

dose.survival: Extract interval-censored dose tolerance data from a dose titration study

Description

Constructs a Surv object from a dose-escalation experiment, using interval-censoring constructs of type='interval2'.

Usage

dose.survival(de)

Value

A Surv object of type='interval2'

Arguments

de

A data frame describing a dose-titration study

Author

David C. Norris

See Also

dose.survfit

Examples

CV <- 0.7; mean_mtd <- 1.0
shape <- CV^-2; scale <- mean_mtd/shape
trial <- new("DE", doses=0.25 * 1.4^(0:6),
             MTDi=rgamma(24, shape=shape, scale=scale),
             units="mg")
trial <- titration(trial, periods=10)
dose.survival(trial@data)