DoseFinding (version 0.5-5)

getInit: Starting values for non-linear parameters.

Description

Calculates starting values for non-linear parameters in non-linear models. Note that starting values are only needed if optimizer = "nls" in the MCPMod function.

Usage

getInit(data,
           model = c("emax", "exponential", "logistic", "betaMod", "sigEmax"),
           scal, weights, addCovars)

Arguments

data

Data frame containing dose response data set. The dose column should be called "dose", the response column "resp", all other variables possibly referenced in addCovars should also be present.

model

Character specifying the model.

scal

Scal parameter for betaMod model.

weights

Numeric specifying weights for fitting.

addCovars

Formula specifying the additional covariates.

Value

• Starting value

References

Pinheiro, J. C., Bretz, F., and Branson, M. (2006). Analysis of dose-response studies - modeling approaches, in N. Ting (ed.). Dose Finding in Drug Development, Springer, New York, pp. 146--171

See Also

fitDRModel