adu340_4small

<p>adu340_4small is the result from a calcium-buffering
experiment performed in a glomerulus of the Cockroach
(<em>Periplaneta americana</em>) antennal lobe, where the
projection neurons were imaged using Fura-2. Calcium
variations were measured through time and space at 340 nm.</p>

A two-stage procedure for the denoising and clustering of stack of noisy images acquired over time. Clustering only assumes that the data contain an unknown but small number of dynamic features. The method first denoises the signals using local spatial and full temporal information. The clustering step uses the previous output to aggregate voxels based on the knowledge of their spatial neighborhood. Both steps use a single keytool based on the statistical comparison of the difference of two signals with the null signal. No assumption is therefore required on the shape of the signals. The data are assumed to be normally distributed (or at least follow a symmetric distribution) with a known constant variance. Working pixelwise, the method can be time-consuming depending on the size of the data-array but harnesses the power of multicore cpus.

Yves Rozenholc

DynClust

adu340_4small: Calcium-imaging dataset using Fura-2

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