Body weights of a 90-day chronic toxicological study on rats with a control and three
dose groups.

datasets

Treatments of a one-way layout, being equivalent to a control,
can be selected with this package. Bonferroni adjusted "two one-sided
t-tests" (TOST) and related simultaneous confidence intervals are given for
both differences or ratios of means of normally distributed data. For the
case of equal variances and balanced sample sizes for the treatment groups,
the single-step procedure of Bofinger and Bofinger (1995)
<doi:10.1111/j.2517-6161.1995.tb02058.x> can be chosen. For non-normal data,
the Wilcoxon test is applied.

Mario Hasler

Equivalence to Control

BW function

A data frame with 60 observations on the following 2 variables.<dl class="dl-horizontal">
 <dt><code>Weight</code></dt><dd>a numeric vector containing the bodyweights of rats</dd>
 <dt><code>Dose</code></dt><dd>a factor with levels <code>1</code> <code>2</code> <code>3</code> <code>4</code>,
 specifying the dose groups, where <code>1</code> is the control group</dd>
 </dl>

Format

Body weights measured in a toxicological study — BW

A data frame with 60 observations on the following 2 variables.<dl class='dl-horizontal'>
 <dt><code>Weight</code></dt><dd>a numeric vector containing the bodyweights of rats</dd>
 <dt><code>Dose</code></dt><dd>a factor with levels <code>1</code> <code>2</code> <code>3</code> <code>4</code>,
 specifying the dose groups, where <code>1</code> is the control group</dd>
 </dl>

BW: Body weights measured in a toxicological study

Description

Usage

Arguments

Format

Examples