BrCa: Clinical status, relapse, metastasis and death in 2982 women with breast cancer.

Description

This dataset is a transformation of the example dataset used by Crowther and Lambert in their multistate paper.

Usage

data(BrCa)

Arguments

Format

A data frame with 2982 observations on the following 17 variables:

pid: Person-id; numeric
year: Calendar year of diagnosis
age: Age at diagnosis
meno: Menopausal status; a factor with levels pre post
size: Tumour size; a factor with levels <=20 mm >20-50 mm >50 mm
grade: Tumour grade; a factor with levels 2 3
nodes: Number of positive lymph nodes, a numeric vector
pr: Progesteron receptor level
pr.tr: Transformed progesteron level
er: Estrogen receptor level
hormon: Hormon therapy at diagnosis; a factor with levels no yes
chemo: Chemotherapy treatment; a factor with levels no yes
tor: Time of relapse, years since diagnosis
tom: Time of metastasis, years since diagnosis
tod: Time of death, years since diagnosis
tox: Time of exit from study, years since diagnosis
xst: Vital status at exit; a factor with levels Alive Dead

Details

The dataset has been modified to contain the times (since diagnosis) of the events of interest, to comply with the usual structure of data.

References

The data were used as example in the paper by Crowther and Lambert: Parametric multistate survival models: Flexible modelling allowing transition-specific distributions with application to estimating clinically useful measures of effect differences; Stat Med 36 (29), pp 4719-4742, 2017. (No, it is not the paper, just the title.)

A parallel analysis using the Lexis machinery is available as: http://bendixcarstensen.com/AdvCoh/papers/bcMS.pdf

Examples

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data(BrCa)

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