geno-class

Class contains all information needed to generate a kernel matrix for
genotype data.

classes

A computationally efficient and statistically rigorous fast
Kernel Machine method for multi-kernel analysis. The approach is based on
a low-rank approximation to the nuisance effect kernel matrices. The
algorithm is applicable to continuous, binary, and survival traits and
is implemented using the existing single-kernel analysis software 'SKAT'
and 'coxKM'. 'coxKM' can be obtained from
<https://github.com/lin-lab/coxKM>.

Shannon Holloway

FastKM

A Fast Multiple-Kernel Method Based on a Low-Rank Approximation

geno-class function

Objects can be created by calls of the form <code>new("geno", ...)</code>.

Objects from the Class

<dl class="dl-horizontal">
 <dt><code>mat</code>:</dt><dd>Object of class <code>"matrix or NULL"</code>; 
 one-column-per-marker formatted genotype data.</dd>
 <dt><code>kernel</code>:</dt><dd>Object of class <code>"character"</code>; 
 type of kernel to generate.</dd>
 <dt><code>weights</code>:</dt><dd>Object of class <code>"matrix"</code>;
 weights to be used when generating
 kernel matrix.</dd>
 </dl>

Slots

No methods defined with class "geno" in the signature.

Methods

Class <code>"geno"</code> — geno-class

<dl class='dl-horizontal'>
 <dt><code>mat</code>:</dt><dd>Object of class <code>"matrix or NULL"</code>; 
 one-column-per-marker formatted genotype data.</dd>
 <dt><code>kernel</code>:</dt><dd>Object of class <code>"character"</code>; 
 type of kernel to generate.</dd>
 <dt><code>weights</code>:</dt><dd>Object of class <code>"matrix"</code>;
 weights to be used when generating
 kernel matrix.</dd>
 </dl>

geno-class: Class `"geno"`

Description

Arguments

Objects from the Class

Slots

Methods

See Also

Examples