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GLMaSPU (version 1.0)

An Adaptive Test on High Dimensional Parameters in Generalized Linear Models

Description

Several tests for high dimensional generalized linear models have been proposed recently. In this package, we implemented a new test called adaptive sum of powered score (aSPU) for high dimensional generalized linear models, which is often more powerful than the existing methods in a wide scenarios. We also implemented permutation based version of several existing methods for research purpose. We recommend users use the aSPU test for their real testing problem. You can learn more about the tests implemented in the package via the following papers: 1. Pan, W., Kim, J., Zhang, Y., Shen, X. and Wei, P. (2014) A powerful and adaptive association test for rare variants, Genetics, 197(4). 2. Guo, B., and Chen, S. X. (2016) . Tests for high dimensional generalized linear models. Journal of the Royal Statistical Society: Series B. 3. Goeman, J. J., Van Houwelingen, H. C., and Finos, L. (2011) . Testing against a high-dimensional alternative in the generalized linear model: asymptotic type I error control. Biometrika, 98(2).

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Version

Install

install.packages('GLMaSPU')

Monthly Downloads

130

Version

1.0

License

GPL-2

Maintainer

Last Published

December 9th, 2016

Functions in GLMaSPU (1.0)

Goeman_perm

Resample based Goeman test.
HDGLM_perm

Resample based HDGLM test.
aSPU_perm

Resample based Sum of Powered Score (SPU) tests and adaptive SPU (aSPU) test.
generate_data

Generate data for generalized linear models in simulation.
GLMaSPU-package

An Adaptive Test on High Dimensional Parameters in Generalized Linear Models
aSPU_apval

Asymptotic based Sum of Powered Score (SPU) tests and adaptive SPU (aSPU) test.