GOSemSim (version 1.28.1)

GOSemSim-package: Gene Ontology-based Sematic Similarity Measures

Description

Implementation of semantic similarity measures to estimate the functional similarities among Gene Ontology terms and gene products

Details

Quantitative measure of functional similarities among gene products is important for post-genomics study. and widely used in gene function prediction, cluster analysis and pathway modeling. This package is designed to estimate the GO terms' and genes' semantic similarities. Implemented five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively. Support many species, including Anopheles, Arabidopsis, Bovine, Canine, Chicken, Chimp, E coli strain K12 and strain Sakai, Fly, Human, Malaria, Mouse, Pig, Rhesus, Rat, Worm, Xenopus, Yeast, Zebrafish.

Package:

GOSemSim

Type:

Package

Version:

1.24.0

Date:

09-11-2012

biocViews:

GO, Clustering, Pathways, Anopheles_gambiae, Arabidopsis_thaliana, Bos_taurus, Caenorhabditis_elegans, Canis_familiaris, Danio_rerio, Drosophila_melanogaster, Escherichia_coli, Gallus_gallus, Homo_sapiens, Mus_musculus, Pan_troglodytes, Plasmodium_falciparum, Rattus_norvegicus, Saccharomyces_cerevisiae, Streptomyces_coelicolor, Sus_scrofa, Xenopus_laevis

Depends:

Imports:

methods, AnnotationDbi, GO.db, org.Hs.eg.db, org.Ag.eg.db, org.At.tair.db, org.Bt.eg.db, org.Ce.eg.db, org.Cf.eg.db, org.Dm.eg.db, org.Dr.eg.db, org.EcK12.eg.db, org.EcSakai.eg.db, org.Gg.eg.db, org.Mm.eg.db, org.Mmu.eg.db, org.Pf.plasmo.db, org.Pt.eg.db, org.Rn.eg.db, org.Sc.sgd.db, org.Sco.eg.db, org.Ss.eg.db, org.Tgondii.eg.db, org.Xl.eg.db

Suggests:

clusterProfiler

License:

Artistic-2.0

References

Yu et al. (2010) GOSemSim: an R package for measuring semantic similarity among GO terms and gene products Bioinformatics (Oxford, England), 26:7 976--978, April 2010. ISSN 1367-4803 http://bioinformatics.oxfordjournals.org/cgi/content/abstract/26/7/976 PMID: 20179076

See Also

goSim mgoSim geneSim mgeneSim clusterSim mclusterSim