The function takes the results from a functional analysis (for
example DAVID) and combines it with a list of selected genes and their
logFC. The resulting data frame can be used as an input for various ploting
functions.
Usage
circle_dat(terms, genes)
Arguments
terms
A data frame with columns for 'category', 'ID', 'term', adjusted
p-value ('adj_pval') and 'genes'
genes
A data frame with columns for 'ID', 'logFC'
Details
Since most of the gene- annotation enrichment analysis are based on
the gene ontology database the package was build with this structure in
mind, but is not restricted to it. Gene ontology is structured as an
acyclic graph and it provides terms covering different areas. These terms
are grouped into three independent categories: BP (biological
process), CC (cellular component) or MF (molecular function).
The "ID" and "term" columns of the terms data frame refer to the ID
and term description, whereas the ID is optional.
The "ID" column of the genes data frame can contain any unique
identifier. Nevertheless, the identifier has to be the same as in "genes"
from terms.