data("Simulated_data")
FamID
Child
, Parent
and Sibling
Y
No
and Yes
delta
p0G
Marder, K., Wang, Y., Alcalay, R. N., Mejia-Santana, H., Tang, M. X., Lee, A., ... & Miravite, J. (2015). Age-specific penetrance of LRRK2 G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 Consortium. Neurology, 85(1), 89--95.
Qin, J., Garcia, T., Ma, Y., Tang, M., Marder, K. & Wang, Y. (2014). Combining isotonic regression and EM algorithm to predict genetic risk under monotonicity constraint. The Annals of Applied Statistics 8(2), 1182-1208.
Sieve_NPMLE_Switch()
, Sieve_NPMLE_Bootstrap()
, EM_PAVA_Func()
.