# simulated data to use
set.seed(10)
ds <- data.frame(
ftime = rexp(200),
fstatus = sample(0:1, 200, replace = TRUE),
x1 = runif(200),
x2 = runif(200),
x3 = runif(200)
)
library(survival)
library(rms)
dd <- datadist(ds)
options(datadist = "dd")
s <- Surv(ds$ftime, ds$fstatus == 1)
fit <- cph(s ~ x1 + x2 + x3, data = ds)
if (isFitCoxPH(fit)) {
print("Correct, the cph is of cox PH hazard type")
}
fit <- coxph(s ~ x1 + x2 + x3, data = ds)
if (isFitCoxPH(fit)) {
print("Correct, the coxph is of cox PH hazard type")
}
library(cmprsk)
set.seed(10)
ftime <- rexp(200)
fstatus <- sample(0:2, 200, replace = TRUE)
cov <- matrix(runif(600), nrow = 200)
dimnames(cov)[[2]] <- c("x1", "x2", "x3")
fit <- crr(ftime, fstatus, cov)
if (isFitCoxPH(fit)) {
print(paste(
"Correct, the competing risk regression is",
"considered a type of cox regression",
"since it has a Hazard Ratio"
))
}
# ** Borrowed code from the lrm example **
# Fit a logistic model containing predictors age, blood.pressure, sex
# and cholesterol, with age fitted with a smooth 5-knot restricted cubic
# spline function and a different shape of the age relationship for males
# and females.
n <- 1000 # define sample size
set.seed(17) # so can reproduce the results
age <- rnorm(n, 50, 10)
blood.pressure <- rnorm(n, 120, 15)
cholesterol <- rnorm(n, 200, 25)
sex <- factor(sample(c("female", "male"), n, TRUE))
label(age) <- "Age" # label is in Hmisc
label(cholesterol) <- "Total Cholesterol"
label(blood.pressure) <- "Systolic Blood Pressure"
label(sex) <- "Sex"
units(cholesterol) <- "mg/dl" # uses units.default in Hmisc
units(blood.pressure) <- "mmHg"
# To use prop. odds model, avoid using a huge number of intercepts by
# grouping cholesterol into 40-tiles
# Specify population model for log odds that Y = 1
L <- .4 * (sex == "male") + .045 * (age - 50) +
(log(cholesterol - 10) - 5.2) * (-2 * (sex == "female") + 2 * (sex == "male"))
# Simulate binary y to have Prob(y = 1) = 1/[1+exp(-L)]
y <- ifelse(runif(n) < plogis(L), 1, 0)
cholesterol[1:3] <- NA # 3 missings, at random
ddist <- datadist(age, blood.pressure, cholesterol, sex)
options(datadist = "ddist")
fit_lrm <- lrm(y ~ blood.pressure + sex * (age + rcs(cholesterol, 4)),
x = TRUE, y = TRUE
)
if (isFitLogit(fit_lrm) == TRUE) {
print("Correct, the lrm is a logistic regression")
}
fit_lm <- lm(blood.pressure ~ sex)
if (isFitLogit(fit_lm) == FALSE) {
print("Correct, the lm is not a logistic regression")
}
fit_glm_logit <- glm(y ~ blood.pressure + sex * (age + rcs(cholesterol, 4)),
family = binomial()
)
if (isFitLogit(fit_glm_logit) == TRUE) {
print("Correct, the glm with a family of binomial is a logistic regression")
}
fit_glm <- glm(blood.pressure ~ sex)
if (isFitLogit(fit_glm) == FALSE) {
print("Correct, the glm without logit as a family is not a logistic regression")
}
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