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HMMcopy (version 1.14.0)

Copy number prediction with correction for GC and mappability bias for HTS data

Description

Corrects GC and mappability biases for readcounts (i.e. coverage) in non-overlapping windows of fixed length for single whole genome samples, yielding a rough estimate of copy number for furthur analysis. Designed for rapid correction of high coverage whole genome tumour and normal samples.

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Version

Version

1.14.0

License

GPL-3

Maintainer

Daniel Lai

Last Published

February 15th, 2017

Functions in HMMcopy (1.14.0)

HMMcopy internal functions

HMMcopy internal functions
HMMcopy Segmentation

Segmentation and classification of copy number profiles
WIG Output Functions

WIG Output Functions
wigsToRangedData

Parsing and sorting of uncorrected read and sequence information files
WIG Import Functions

WIG Import Functions
HMMcopy Visualization

Visualization functions for correctReadcount results
HMMcopy-package

Bias-free copy number estimation and robust CNA detection in tumour samples from WGS HTS data
HMMcopy example dataset

HMMcopy example dataset
correctReadcount

Readcount correction for GC and mappability bias