INSPEcT (version 1.2.2)

compareSteady: Generate an object of class INSPEcT_diffsteady from two objects of class INSPEcT

Description

Generate an object of class INSPEcT_diffsteady from two objects of class INSPEcT

This method compares two object of class INSPEcT in order to identify differential usage of synthesis, processing or degradation rates in two different steady-state conditions. The two INSPEcT objects must have been profiled with replicates in order to provide a statistical significance to the differences between their rates.

Usage

compareSteady(inspectIds1, inspectIds2)
"compareSteady"(inspectIds1, inspectIds2)

Arguments

inspectIds1

An object of calss INSPEcT

inspectIds2

A second object of calss INSPEcT

Value

An object of class INSPEcT_diffsteady which contains both the absolute quantification of the rates as well as the comparison with the statistcal significance associated for each gene and rate. (See INSPEcT_diffsteady-class)

Examples

## load data
data('simRates', package='INSPEcT')
data('simData3rep', package='INSPEcT')
## generate a new data set with 3 replicate to make the comparison
newTpts <- c(0, 1/6)
simData3rep_2 <- makeSimDataset(simRates, newTpts, 3, seed=2)
## compare
diffrates <- compareSteady(simData3rep, simData3rep_2)
## visualize results
diffrates