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ISwR (version 2.0-9)

philion: Dose response data

Description

Four small experiments with the purpose of estimating the EC50 of a biological dose-response relation.

Usage

philion

Arguments

Format

A data frame with 30 observations on the following 3 variables:

experiment

a numeric vector; codes 1 through 4 denote the experiment number.

dose

a numeric vector, the dose.

response

a numeric vector, the response (counts).

Details

These data were discussed on the R mailing lists, initially suggesting a log-linear Poisson regression, but actually a relation like \(y=y_{\rm max}/(1+(x/\beta)^\alpha)\) is more suitable.

References

https://stat.ethz.ch/pipermail/r-help/2003-July/036828.html (Thread on R-help mailing list: "inverse prediction and Poisson regression", started by Vincent Philion on July 25, 2003.)