Plot of the data points and the sample means at each dose
Usage
IsoPlot(x, y, type=c("continuous", "ordinal"), add.curve = FALSE)
Arguments
x
indicates the dose levels
y
is the gene expression for one gene
type
specifies the dose levels to "continuous" or "ordinal". The default is "continous".
add.curve
specifies whether a fitted isotonic regression curve with a likely direction is added or not. The default is FALSE.
Value
Plot of the data points, the sample means for each dose (either as continuous or ordinal), and a fitted isotonic regression curve (optional) is produced.
References
Lin D., Shkedy Z., Yekutieli D., Amaratunga D., and Bijnens,
L. (editors). (2012) Modeling Dose-response Microarray
Data in Early Drug Development Experiments Using
R. Springer.
IsoGene: An R Package for Analyzing Dose-response Studies in Microarray Experiments, Pramana S., Lin D., Haldermans P., Shkedy Z., Verbeke T., De Bondt A., Talloen W., Goehlmann H., Bijnens L. 2010, R Journal 2/1.