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KMgene (version 1.3)

Gene-Based Association Analysis for Complex Traits

Description

Gene based association test between a group of SNPs and traits including familial (both continuous and binary) traits, multivariate continuous (both independent and familial) traits and longitudinal continuous traits. Part of methods were previously published in Maity et al (2012) , Chen et al (2013) , Yan et al (2015) , Yan et al (2015) and Yan et al (2015) .

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Version

Install

install.packages('KMgene')

Monthly Downloads

32

Version

1.3

License

GPL (>= 2)

Maintainer

Qi Yan

Last Published

June 2nd, 2020

Functions in KMgene (1.3)

Optimal KM for Quantitative Traits in Longitudinal GWAS Data (calculate p-value)

KM for continuous Traits in Familial GWAS Data (calculate p-value)

This is continuous multivariate family data with numeric IDs

KM for Quantitative Traits in Multivariate Family GWAS Data (calculate p-value)

MKMO_Null_Model

Optimal KM for Multiple Quantitative Traits in GWAS Data (fit null model)

Optimal KM for continuous Traits in Familial GWAS Data (calculate p-value)

KM for Multiple Quantitative Traits in GWAS Data (fit null model)

Optimal KM for Quantitative Traits in Multivariate Family GWAS Data (calculate p-value)

This is continuous longitudinal data with character IDs

Optimal KM for Quantitative Traits in Multivariate GWAS Data (calculate p-value)

KM for Quantitative Traits in Multivariate GWAS Data (calculate p-value)

KM for Quantitative Traits in Longitudinal GWAS Data (fit null model)

This is survival data

KM for Traits by Time Interaction in Longitudinal GWAS Data

LKMO_Null_Model

Optimal KM for Quantitative Traits in Longitudinal GWAS Data (fit null model)

KM for Binary Traits in Familial GWAS Data (calculate p-value)

MFKMO_Null_Model

Optimal KM for Quantitative Traits in Multivariate Family GWAS Data (fit null model)

Optimal KM for Non-continuous Traits in Familial GWAS Data (calculate p-value)

FbKMO_Null_Model

Optimal KM for Binary Traits in Familial GWAS Data (fit null model)

FbKM_Null_Model

KM for Binary Traits in Familial GWAS Data (fit null model)

KM for Survival Traits in GWAS Data (fit null model)

This is continuous longitudinal data with numeric IDs

MFKM_Null_Model

KM for Quantitative Traits in Multivariate Family GWAS Data (fit null model)

This is continuous longitudinal data with numeric IDs

This is continuous multivariate data with numeric IDs

This is continuous multivariate data with character IDs

FKMO_Null_Model

Optimal KM for continuous Traits in Familial GWAS Data (fit null model)

This is continuous family data numeric IDs

This is continuous family data with character IDs

KM for continuous Traits in Familial GWAS Data (fit null model)

KM for Survival Traits in GWAS Data (calculate p-value)

KM for Quantitative Traits in Longitudinal GWAS Data (calculate p-value)

This is continuous multivariate family data with character IDs

This is binary family data with character IDs

This is binary family data numeric IDs