example_data


Contains 20 genes across 564 single-cell sequencing experiments, sorted by pseudotime using the package Monocle.


datasets

Advances in sequencing technology now allow researchers to capture the expression profiles of individual cells. Several algorithms have been developed to attempt to account for these effects by determining a cell's so-called `pseudotime', or relative biological state of transition. By applying these algorithms to single-cell sequencing data, we can sort cells into their pseudotemporal ordering based on gene expression. LEAP (Lag-based Expression Association for Pseudotime-series) then applies a time-series inspired lag-based correlation analysis to reveal linearly dependent genetic associations.

Alicia T Specht

LEAP

Constructing Gene Co-Expression Networks for Single-Cell
RNA-Sequencing Data Using Pseudotime Ordering

example_data function

A data frame with 20 observations on 564 variables.

Format

 Shalek AK, Satija R., Shuga J., Trombetta J.J. et al. (2014) Single-cell RNA-seq reveals dynamic paracrine control of cellular variation. Nature, 510(7505), 363-369. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193940/

example_data: Numeric data frame of example data

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