MAICtools (version 0.1.1)
Performing Matched-Adjusted Indirect Comparisons (MAIC)
Description
A generalised workflow for Matching-Adjusted Indirect
Comparison (MAIC) analysis, which supports both anchored and
non-anchored MAIC methods. In MAIC, unbiased trial outcome comparison
is achieved by weighting the subject-level outcomes of the
intervention trial so that the weighted aggregate measures of
prognostic or effect-modifying variables match those of the comparator
trial. Measurements supported include time-to-event (e.g., overall
survival) and binary (e.g., objective tumor response). The method is
described in Signorovitch et al. (2010)
and Signorovitch et al. (2012)
.