A subset of the data used by (Biesheuvel and Hothorn, 2002). 
Except for the dose and the response variable all variables from the original data set
are removed. 
The data are part of a dose ranging trial on a compound for the treatment of the
irritable bowel syndrome with four active treatment arms,
corresponding to doses 1,2,3,4 and placebo. Note that the original dose levels
have been blinded in this data set for confidentiality. The primary endpoint
was a baseline adjusted abdominal pain score with larger values
corresponding to a better treatment effect. In total 369 patients
completed the study, with nearly balanced allocation across the
doses.

datasets

Implements a methodology for the design and analysis of dose-response studies that
combines aspects of multiple comparison procedures and modeling approaches
(Bretz, Pinheiro and Branson, 2005, Biometrics 61, 738-748, <doi: 10.1111/j.1541-0420.2005.00344.x>).
The package provides tools for the analysis of dose finding trials as well as a variety
of tools necessary to plan a trial to be conducted with the MCP-Mod methodology.
Please note: The 'MCPMod' package will not be further developed, all future development of
the MCP-Mod methodology will be done in the 'DoseFinding' R-package.

Bjrn Bornkamp

MCPMod

Design and Analysis of Dose-Finding Studies

IBS function

A data frame with 369 observations on the following 2 variables.<dl class="dl-horizontal">
 <dt><code>dose</code></dt><dd>a numeric vector</dd>
 <dt><code>resp</code></dt><dd>a numeric vector</dd>
 </dl>

Format

Irritable Bowel Syndrome Dose Response data — IBS

A data frame with 369 observations on the following 2 variables.<dl class='dl-horizontal'>
 <dt><code>dose</code></dt><dd>a numeric vector</dd>
 <dt><code>resp</code></dt><dd>a numeric vector</dd>
 </dl>

IBS: Irritable Bowel Syndrome Dose Response data

Description

Usage

Arguments

Format