Data on an experiment to examine the effect of a antagonist MDL 72222
on the change in blood pressure experienced with increasing dosage of
phenylbiguanide are described in Ludbrook (1994) and analyzed
in Venables and Ripley (1999, section 8.8). Each of five rabbits was exposed to
increasing doses of phenylbiguanide after having either a placebo or
the HD5-antagonist MDL 72222 administered.