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MHTrajectoryR (version 1.0.1)

Bayesian Model Selection in Logistic Regression for the Detection of Adverse Drug Reactions

Description

Spontaneous adverse event reports have a high potential for detecting adverse drug reactions. However, due to their dimension, the analysis of such databases requires statistical methods. We propose to use a logistic regression whose sparsity is viewed as a model selection challenge. Since the model space is huge, a Metropolis-Hastings algorithm carries out the model selection by maximizing the BIC criterion.

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Install

install.packages('MHTrajectoryR')

Monthly Downloads

121

Version

1.0.1

License

GPL (>= 2)

Maintainer

Last Published

April 5th, 2016

Functions in MHTrajectoryR (1.0.1)

Analyze_oneAE

Signal detection using via variable selection in logistic regression. The Bayesian Information Criterion maximization is assessed using Metropolis-Hastings algorithm.
OmopReference

The OMOP reference set
exampleDrugs

A simulated data
exampleAE

A simulated data