MRsurv (version 0.2)

FTR.data: These data were extracted from the DIVAT data bank for first kidney transplant recipients.

Description

Data were extracted from the DIVAT cohort. It corresponds to the reference sample constituted by first transplant recipients (FTR).

Usage

data(FTR.data)

Format

A data frame with the 4 following variables.

Tps.Evt

This numeric vector provides the post-transplantation time (in days).

Evt

This numeric vector provides the indicator of graft failure at the end of the follow-up (1 for failure and 0 for right censoring).

ageR2cl

This numeric vector provides the recipient age at transplantation (1 for older than 55 years and 0 otherwise).

sexeR

This numeric vector provides the recipient gender (1 for men and 0 for women).

Details

First transplant recipients (FTR) constituted the reference group. Recipients older than 18 years at the date of transplantation between 1996 and 2010 were selected from the French DIVAT (www.divat.fr/en) multicentric prospective cohort. Only recipients with a maintenance therapy with calcineurin inhibitors, mammalian target of rapamycin inhibitors or belatacept, in addition to mycophenolic acid and steroid were included. Simultaneous transplantations were excluded. Two explicative variables are proposed: recipient age at transplantation and recipient gender.

References

K. Trebern-Launay, M. Giral, J. Dantal and Y. Foucher. Comparison of the risk factors effects between two populations: two alternative approaches illustrated by the analysis of first and second kidney transplant recipients. BMC Med Res Methodol. 2013 Aug 6;13:102.

Examples

data(FTR.data)

# Compute a Cox PH model with both explicative variables
cox.FTR<-coxph(Surv(Tps.Evt/365.24, Evt) ~ ageR2cl + sexeR, data=FTR.data)
summary(cox.FTR)