MRsurv (version 0.2)

MRsurv-package: Multiplicative-regression model for relative survival.

Description

This package computes multiplicative-regression model for relative survival.

Details

Relative survival models are traditionally used in the evaluation of mortality related to chronic diseases, taking into account the expected mortality of general population (life table by gender, calendar year and age). Here, we propose here an adaptation of a multiplicative-regression model for relative survival to study the heterogeneity of risk factors between two groups of patients. These developments were motivated by the analysis of factors associated with the time to graft failure (return-to-dialysis or patient death) in second kidney transplant recipients compared to first kidney transplant recipients. The parameters' estimation is based on partial likelihood maximization and Monte-Carlo simulations associated with bootstrap re-sampling yields to obtain the corresponding standard deviations.

Package:

MRsurv

Type:

Package

Version:

0.2

Date:

2013-10-31

License:

GPL (>=2)

LazyLoad:

yes

MRsurvival

Compute a MRS model to compare the risk factors between a

$ \mbox{ } $

reference and a relative population.

FTR.data

These data were extracted from the DIVAT data bank for first

$ \mbox{ } $

kidney transplant recipients (reference group).

STR.data

These data were extracted from the DIVAT data bank for second

$ \mbox{ } $

kidney transplant recipients (relative group).

References

Andersen P, Borch-Johnsen K, Deckert T, Green A, Hougaard P, Keiding N, Kreiner S. A cox regression model for the relative mortality and its application to diabetes mellitus survival data. Biometrics Dec 1985; 41(4):921-932.

K. Trebern-Launay, M. Giral, J. Dantal and Y. Foucher. Comparison of the risk factors effects between two populations: two alternative approaches illustrated by the analysis of first and second kidney transplant recipients. BMC Med Res Methodol. 2013 Aug 6;13:102.

See Also

URL: http://www.divat.fr