mbe_boot

Internal function for calculating standard error of mode-based estimate.

internal

Encodes several methods for performing Mendelian randomization
analyses with summarized data. Summarized data on genetic associations with the
exposure and with the outcome can be obtained from large consortia. These data
can be used for obtaining causal estimates using instrumental variable methods.

Stephen Burgess

MendelianRandomization

Mendelian Randomization Package

Olena Yavorska

James Staley

Fernando Hartwig

Jim Broadbent

Christopher Foley

Andrew Grant

Amy Mason

Ting Ye

Haoran Xue

Zhaotong Lin

Siqi Xu

Ashish Patel

Hyunseung Kang

Sheng Wang

Ville Karhunen

mbe_boot function

<dl><dt>BetaIV.in</dt>
<dd>Ratio causal estimates for each genetic variant considered individually.</dd>
<dt>seBetaIV.in</dt>
<dd>Standard errors of ratio causal estimates.</dd>
<dt>iterations.in</dt>
<dd>Number of bootstrap iterations.</dd>
<dt>phi.in</dt>
<dd>Bandwidth multiplication factor.</dd></dl>

Arguments

Mode-based estimate (Hartwig) bootstrap function — mbe_boot

<dl>

<dt>BetaIV.in</dt>
<dd>Ratio causal estimates for each genetic variant considered individually.</dd>


<dt>seBetaIV.in</dt>
<dd>Standard errors of ratio causal estimates.</dd>


<dt>iterations.in</dt>
<dd>Number of bootstrap iterations.</dd>


<dt>phi.in</dt>
<dd>Bandwidth multiplication factor.</dd>

</dl>

Mode-based estimate (Hartwig) bootstrap function

mbe_boot: Mode-based estimate (Hartwig) bootstrap function

Description

Usage

Value

Arguments

Details

Examples