initializeMiRSEA

Getenvir

These functions internally called by other functions in the package <code>MiRSEA</code> and not meant to be called by the user.

internal

MiRSEA-internal

The tools for 'MicroRNA Set Enrichment Analysis' can identify risk pathways(or prior gene sets) regulated by microRNA set in the context of microRNA expression data. (1) This package constructs a correlation profile of microRNA and pathways by the hypergeometric statistic test. The gene sets of pathways derived from the three public databases (Kyoto Encyclopedia of Genes and Genomes ('KEGG'); 'Reactome'; 'Biocarta') and the target gene sets of microRNA are provided by four databases('TarBaseV6.0'; 'mir2Disease'; 'miRecords'; 'miRTarBase';). (2) This package can quantify the change of correlation between microRNA for each pathway(or prior gene set) based on a microRNA expression data with cases and controls. (3) This package uses the weighted Kolmogorov-Smirnov statistic to calculate an enrichment score (ES) of a microRNA set that co-regulate to a pathway , which reflects the degree to which a given pathway is associated with the specific phenotype. (4) This package can provide the visualization of the results.

Junwei Han

MiRSEA

'MicroRNA' Set Enrichment Analysis

MiRSEA-internal function

Junwei Han<a href="/link/hanjunwei1981%40163.com?package=MiRSEA&version=1.1.1" data-mini-rdoc="MiRSEA::hanjunwei1981@163.com">hanjunwei1981@163.com</a>,Siyao Liu <a href="/link/liusiyao29%40163.com?package=MiRSEA&version=1.1.1" data-mini-rdoc="MiRSEA::liusiyao29@163.com">liusiyao29@163.com</a>

Author

MiRSEA internal functions — MiRSEA-internal

Junwei Han<a href='mailto:hanjunwei1981@163.com'>hanjunwei1981@163.com</a>,Siyao Liu <a href='mailto:liusiyao29@163.com'>liusiyao29@163.com</a>

MiRSEA-internal: MiRSEA internal functions

Description

Usage

Arguments

Author