MultEq (version 2.4)

MultEq-package: Equivalence for multiple endpoints

Description

The package provides tests and confidence intervals for comparing two treatments when there is more than one primary response variable (endpoint). The step-up procedure of Quan et al. (2001) is both applied for differences and extended to ratios of means of normally distributed data with equal group variances. A related single-step procedure is also available.

Details

Package:	MultEq
Type:	Package
Version:	2.4
Date:	2022-03-02
License:	GPL
LazyLoad:	yes

• multeq.diffEquivalence tests and related confidence intervals for differences of normal means of multiple endpoints

• multeq.ratEquivalence tests and related confidence intervals for ratios of normal means of multiple endpoints

• clinicData set of body measurements in a clinical study

References

Quan et al. (2001): Assessmant of equivalence on multiple endpoints, Statistics in Medicine 20, 3159-3173

Examples

# NOT RUN {
data(clinic)

comp <- multeq.diff(data=clinic,grp="fact",method="step.up",margin.up=rep(0.6,5),
                    margin.lo=-rep(0.6,5))
summary(comp)
# }