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OptInterim (version 3.0.1)

Optimal Two and Three Stage Designs for Single-Arm and Two-Arm Randomized Controlled Trials with a Long-Term Binary Endpoint

Description

Optimal two and three stage designs monitoring time-to-event endpoints at a specified timepoint

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Version

Install

install.packages('OptInterim')

Monthly Downloads

17

Version

3.0.1

License

GPL (>= 2)

Maintainer

Bo Huang

Last Published

December 12th, 2012

Functions in OptInterim (3.0.1)

OptimDes

Construct Optimal Two-stage or Three-stage Designs with Time-to-event Endpoints Evaluated at a Pre-specified Time
OptimDesControl

Set parameters controlling numerical methods for OptimDes and np.OptimDes
print.OptimDes

Print Objects Output By OptimDes
np.OptimDes

Optimal Two-Stage or Three-Stage Designs with User-specified Combined Sample Size or Study Length
OptInterim-package

Optimal Two and Three Stage Designs with Time-to-event Endpoints Evaluated at a Pre-specified Time.
plot.OptimDes

Plot efficiency of optimal two-stage or three-stage designs as a function of the total sample size or study length
weibull.plot

Plot Weibull Survival Curves
SimDes

Simulation Studies for Two-Stage or Three-Stage Designs from function OptimDes
weibPmatch

Compute the shape or scale parameter for a Weibull distribution so it has a specified event-free rate at a specified time.
FixDes

Construct a Single-stage Design for a time-to-event Endpoint Evaluated at a Pre-specifed Time Versus Either a Known Standard Control or a Randomized Comparative Control
TestStage

Statistical test for two-stage or three-stage designs from function OptimDes