PBImisc (version 1.0)

schizophrenia: Genetic backgroud of schizophrenia

Description

Dataset with genotypes and phenotypes for 98 patients with schizophrenia disorder.

Usage

data(schizophrenia)

Format

data.frame with 98 obs. and 9 variables

NfkB, CD28, IFN

Genotypes for SNP mutations in selected three genes

Dikeos.manic, Dikeos.reality.distortion, Dikeos.depression, Dikeos.disorganization, Dikeos.negative

Dikeos scores for schizophrenia measured in five domains

Dikeos.sum

Sum of Dikeos scores

Source

Artificial dataset generated to be consistent with Dorota F. study

Details

Alleles for two SNPs in genes: Nuclear Factor-Kappa Beta (NfkB) and Cluster of Differentiation 28 (CD28) were examined as well as mental health described by five scales (see Dikeos 2008 for more details).

Examples

data(schizophrenia)
attach(schizophrenia)
interaction.plot(CD28, NfkB, Dikeos.sum)
interaction.plot(NfkB, CD28, Dikeos.sum)
model.tables(aov(Dikeos.sum~NfkB*CD28))