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PK (version 1.3-6)

Rep.tox: Plasma levels in rats following daily intravenous administration in a repeated dose toxicity study

Description

The Rep.tox data frame has 28 rows and 4 columns and gives the plasma levels of 6 rats in a repeated dose toxicity study.

Arguments

Format

This data frame contains the following columns:

id

a numeric vector identifying the animal whose plasma level is measured.

conc

a numeric vector giving the measured plasma level (IU/mL).

time

a numeric vector giving the time since administration (hours).

day

a numeric vector indicating the day the data were collected.

Details

In this study the compound is administered daily to 6 Rats over 14 days. Plasma levels are measured at 7 time points over 12 hours after the first administration and after the 14th administration.