PROFANCY-package

PROFANCY

PROFANCY is a R platform to prioritize candidate disease metabolites by PROFANCY method which extend random walk analysis in the metabolic network with functional pathway nodes

The package can prioritize the candidate disease metabolites based on the assumption
that functionally related metabolites tend to associate with the same or similar
diseases in the context of metabolic pathway. The PROFANCY package (1) prioritizes the
disease metabolites from global functional similarity and local modularity of the
metabolic network; (2) allows users to select default metabolites or input their
interested metabolites as seed nodes or candidate nodes (3) can prioritize the candidate
metabolites in KEGG or EHMN metabolic network.

Qianlan Yao

The package can prioritize candidate disease metabolites based
on global functional relationships between metabolites in the
context of metabolic pathways

PROFANCY-package function

The main goal of PROFANCY is to prioritize candidate disease metabolites by PROFANCY method. This system provides the rank of candidate diseases metabolites which coud be provided by users or this system. 

PROFANCY-package: The PROFANCY package

Description

Arguments

Introduction