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Prunes the CN profile by pruning and merging through hierarchical clustering.
# S3 method for AbstractCBS pruneByHClust(fit, ..., size=NULL, distMethod="euclidean", hclustMethod="ward.D", merge=TRUE, update=TRUE, verbose=FALSE)
Returns a pruned object of the same class.
Arguments passed to cutree, particularly either of thresholds h or k.
cutree
h
k
Arguments (as well as some of ...) passed to *hclustCNs().
...
*hclustCNs()
If TRUE, consecutive segments that belong to the same PSCN cluster will be merged into one large segment.
TRUE
If TRUE, segment means are updated afterwards, otherwise not.
See Verbose.
Verbose
Henrik Bengtsson
if (FALSE) { fitP <- pruneByHClust(fit, h=0.25) }
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