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Peptides (version 1.2.1)

K: The 10 factors from Kidera et al (1985)

Description

The Kidera Factors were originally derived by applying multivariate analysis to 188 physical properties of the 20 amino acids and using dimension reduction techniques. A 10-dimensional vector of orthogonal factors was then obtained for each amino acid.

Usage

data(K)

Arguments

Format

A list with the ten Kidera factors of the 20 amino acids. The first four factors are essentially pure physical properties; the remaining six factors are superpositions of several physical properties, and are labelled for convenience by the name of the most heavily weighted component.
  • Side-chain size,
  • Extended structure preference,
  • Hydrophobicity,
  • Double-bend preference,
  • Partial specific volume,
  • Flat extended preference,
  • Occurrence in alpha region,
  • pK-C,
  • Surrounding hydrophobicity

References

Kidera, A., Konishi, Y., Oka, M., Ooi, T., & Scheraga, H. A. (1985). Statistical analysis of the physical properties of the 20 naturally occurring amino acids. Journal of Protein Chemistry, 4(1), 23-55.