zScales: Compute the Z-scales of a protein sequence
Description
Z-scales are based on physicochemical properties of the AAs including NMR data and thin-layer chromatography (TLC) data.
Usage
zScales(seq)
Value
The computed average of Z-scales of all the amino acids in the corresponding peptide sequence. Each Z scale represent an amino-acid property as follows:
Z4 and Z5: They relate electronegativity, heat of formation, electrophilicity and hardness.
Arguments
seq
An amino-acids sequence
References
Sandberg M, Eriksson L, Jonsson J, Sjostrom M, Wold S: New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids. J Med Chem 1998, 41:2481-2491.