PowerTOST (version 1.2-09)

ct5.1+ct5.2+ct5.3+ct5.4.1: Sample size tables for the classical 2x2 crossover

Description

These data.frames give sample size tables calculated with sampleN.TOST() for the 2x2 design.

Details

The data.frame's can be accessed by their names or by data("name"). ct5.1 is Table 5.1 from Hauschke D., Steinijans V. and Pigeot I. "Bioequivalence studies in Drug Development" John Wiley & Sons, Chichester (2007) Multiplicative model, theta1=0.8, theta2=1.25 (1/theta1), exact ct5.2 is Table 5.2 from the same source Multiplicative model, theta1=0.75, theta2=1.3333 (1/theta1), exact ct5.3 is Table 5.3 from the same source Multiplicative model, theta1=0.9, theta2=1.1111 (1/theta1), exact ct5.4.1 is Table 5.4.1 from Chow S.C., Liu J.P. "Design and Analysis of Bioavailability and Bioequivalence Studies" Third edition, CRC Press, Chapman & Hall, Boca Raton (2009) Additive model, theta1=-0.2, theta2=+0.2 (BE limits 0.80 - 1.20), exact